Dr. David Steenblock developed the World’s first comprehensive state of the art stroke rehabilitation clinic in 1991-94 using HYPERBARIC OXYGEN THERAPY in combination with more conventional physical, occupational and speech therapies. In a review of his work with over 2000 patients 95% of these patients had significant improvements in at least one area of their disabilities. What was especially significant was that these patients had all gone through the standard therapies during previous years but still were suffering so they came from all over the world for his new therapies.
A stroke happens when there is a disruption in blood & oxygen flow in the sufferer’s brain, which results in inflammation, swelling and tissue damage. About 80% of the damage from a stroke is due to the “SECONDARY” EFFECTS” from the swelling that occurs from the initial loss of oxygen.
This swelling constricts the surrounding blood vessels which slows and even stops the blood flow to these areas of the brain that surround the original site of oxygen deficiency. This gradually increasing area of low levels of oxygen expand the area of the stroke which creates 80% of the permanent damage from a stroke. Most if not all of this can be reversed within the first 24 hours after the initial stroke if the patient is treated aggressively to reduce the brain swelling.
In most cases the initial damage is followed by a gradually worsening of the patient’s condition over the next 2-3 days. In some cases the patient will go from being conscious to comatose and death following the initial event. For those old enough to remember- President Nixon’s stroke demonstrates this problem since we all saw him alert on his way to the hospital but then gradually lost consciousness and then died in a coma.
E-medicine has a great article that lays out what emergency room doctors do to minimize acute stroke damage: http://emedicine.medscape.com/article/1159752-overview but in general they do not use hyperbaric oxygen or other methods to reduce the brain swelling. An aggressive neurosurgeon may want to open the skull and it they ask to do that then please do it since this is well proven now to be very helpful in the cases where there is brain swelling. If hyperbaric oxygen is available it must be used every four hours since the brain re-swells every 3 ½ to 4 hours and the HBO reduces the swelling. These every 4 hour HBO treatments need to be given for the first 20-24 hours and then can be given every 12 hours for the next 2-3 weeks if possible when stem cells are not available.
A very good example of this type of brain swelling and how to treat it with HBO is the case of Dorothy, an 80 year old patient of Dr. Steenblock’s who landed first in an ER comatose with paralysis on her left side and an inability to speak who was transferred to Dr Steenblock’s office in an ambulance against the advice of the hospital doctors.
Dr. Steenblock’s plan to halt and reverse the damage in Dorothy’s brain included hyperbaric oxygen therapy. After laying out the possible benefits and risks to Gay, she signed off on everything and Dr. Steenblock had Dorothy do a hyperbaric oxygen therapy session followed by a three (3) hour intravenous “brain repair cocktail”. The IV was created by Dr. Steenblock using his knowledge of the biochemistry of what occurs during an acute stroke. Dorothy also received pulsed magnetic field therapy (PMF) to the back of her head during the course of her intravenous treatment since this increases the blood flow to those areas of the brain that have diminished blood flow.
More HBOT and intravenous treatments followed and by the fifth round Dorothy could move her left arm, and shortly thereafter was able to walk to the bathroom by herself.
By mid-afternoon of her first post-stroke day, just 24 hours since Dorothy entered Dr. Steenblock’s clinic on a gurney, she was able to walk out of the clinic unassisted! After another week of treatments she was driving around town.
But what might Dr. Steenblock’s personalized turnaround approach do for, say, an individual who had a stroke years, even decades before who was plagued by pain, disability or worse? He was handed his first chance to find out when a lady named “Sophie” came to see him.
Wheelchair-bound Sophie had had a stroke ten years previous which had robbed her of her mobility and left her saddled with intractable pain. Like many patients who came to his clinic she had gone to both conventional and integrative medicine physicians, none-of-whom were able to put a dent in her tormenting symptoms.
Dr. Steenblock got Sophia into treatment with hyperbaric oxygen which diminished and then eliminated her pain by the time she completed ten (10) treatments. By her third week of therapy Sophie was able to stand and take a few steps. By the end of her scheduled series of treatments, Sophie was able to walk unassisted out of the clinic and had attained a much higher quality life than anyone including her conventional doctors ever thought possible.
With this success in-hand, Dr. Steenblock then treated and turned things around for scores of other chronic stroke patients.
In 1997 he presented a summary of stroke patient responses to treatment at his clinic in a poster session titled “Improved therapy for Rehabilitation of Stroke” at the National Stroke Association’s ninth annual stroke rehabilitation conference held in Boston, Mass.
And never one to “sit on his laurels”, Dr. Steenblock has expanded his repertoire of effective stroke treatments to include adult or nonembryonic stem cells especially use of a patient’s own revitalized stem cell-rich bone marrow aspirate concentrate or BMAC.
You can get a real feel for how stroke patients respond to Dr. Steenblock’s personalized intervention by seeing what chronic stroke patient Joe Beschen had to say at https://www.youtube.com/watch?v=2JOqwqlUBrs (1m15s video).
Stem Cells & Stem Cell Therapies
You have probably read countless articles and seen a great many televised and posted news segments on stem cells down through the years. But has this left you with a clear understanding of what stem cells are and can do at the therapeutic level? Or have you wound up uncertain or even confused? How about a crash course?
Stem cells differ from other cell types such as skin cell, nerve cells liver cells, heart cells and such because they are unspecialized and are capable of creating copies of themselves, sometimes after being inactive for long periods of time. In addition, when the conditions are right or they are exposed to specific external cues (whether naturally occurring or imposed or introduced such as in an experiment or treatment), these stem cells can be induced to become specific types of cells. In your GI tract and bone marrow, for instance, stem cells regularly divide in order to repair and replace worn out or damaged tissues. On the other hand, stem cells in the heart and pancreas only divide under very circumspect or special conditions.
Dr. Steenblock was an early proponent (1990s) for the use of umbilical cord blood and cord blood stem cells to treat a wide variety of other neurologic and non-neurologic diseases and medical conditions in both children and adults. In 2002 Dr. Steenblock began working closely with highly credentialed physicians in various clinics in Mexico who agreed to utilize pure cord blood stem cells in conjunction with protocols he developed. As part of this work he helped spearhead a pilot study involving eight children with cerebral palsy treated (in Mexico) with cord blood stem cells during 2004-5 which demonstrated both safety and effectiveness.
Then, starting in 2005, Dr. Steenblock pioneered the harvesting and infusion of stem cell rich bone marrow aspirate concentrate (BMAC) along with FDA approved pharmaceutical stem cell activators to successfully treat a wide range of chronic medical conditions and diseases. To this date he has done over 2000 bone marrow treatments with virtually no complications or side effects.
One of the things he discovered is that older, sedentary and/or chronically ill people have bone marrow stem cells that tend to be inactive (senescent).
To counter this Dr. Steenblock prods the patient’s bone marrow to make new, more vital stem cells by giving them injections of the FDA approved stem cell mobilizing drug Neupogen® for five (5) consecutive days. How does this work exactly? The mobilization of huge numbers of mostly senescent (poorly functioning/responsive) stem cells from the marrow switches on natural biological processes that result in the production of new replacement stem cells. What Dr. Steenblock observed is that in two weeks time this revved up replacement activity has produced upwards of 10 times more healthy and more vigorous stem cells than were present prior to the Neupogen® injections!
Clinically this means that stroke patients can be helped significantly with the combination of Neupogen and repetitive bone marrow treatments in combination with hyperbaric oxygen, growth factors, external counterpulsation, periodic acceleration therapy, intravenous and injections of glutathione, methylcobalamin, and PRP (Platelet Rich Plasma).
Dr. Steenblock’s work with revitalizing bone marrow stem cells and then harvesting and using BMAC is but one component of his far-reaching and individualized stem cell clinical work. He also created and uses his own all-natural stem cell mobilizer, Stemgevity, plus other therapies that benefit and/or mobilize stem cells such as hyperbaric oxygen therapy (HBOT) and pulsed electromagnetic field therapy.
Whenever your body sustains an injury or a disease strikes, tissue repair and regeneration mechanisms kick into action. In many instances this process is helped along by the proliferation, migration and differentiation of stem/progenitor cells in the affected tissue or organ. But this isn’t the whole story. Biochemical injury or disease signals make their way throughout the sufferer’s body including the bone marrow where hematopoietic stem cells (HSCs), mesenchymal stem cells (MSCs), endothelial progenitor cells (EPCs) and very small embryonic-like cells (VSELs), are mobilized to varying degrees into the peripheral circulation (A response that has been demonstrated in various experiments and studies with the end result that these various kinds of bone marrow stem cells moved from the marrow into the bloodstream and then into injured tissues, including muscle, heart, kidney, skin, bone, liver and brain).
Once these cells stem cells engraft into diseased or damaged tissues they promote repair and regeneration by secreting various proteins such as growth factors and cytokines.
If you happen to have been injured recently or have a chronic disease, you naturally want to do all you can to support your body’s stem cells and their mobilization. But what if you are not bothered by any sort of health issue? Well, you should not ignore doing things to support the vitality and mobilization response of the stem cells in your tissues and especially bone marrow. And there is a reason for you to be concerned: As we get older — and especially for those of us who are sedentary — bone marrow stem cells become devitalized and inactive or senescent. However, if these inactive stem cells are prodded to mobilize the bone marrow will go to work and replace them with healthier stem cells.
So what things can help mobilize and revitalize stem cells? Here are a few good ones:
- Exercise and other physical activity.
- Work culinary & medicinal (fucoidan-rich) seaweeds and algae into your diet. Among these are kelp, Irish Moss, bladderwrack, laminaria, wakame, kombu, and mozuku.
- Also, consume Noni fruit as well as Acai and Goji berries.
- Use ginger root in tea form and as an ingredient in foods.
- Take supplemental lithium and drink lithium rich water (Lithia water).
Take a stem cell vitality and mobilization support supplement such as Dr. Steenblock’s Stemgevitytm (Click to pull up label including ingredients).
Natural Therapies for Stroke
You’ve probably heard the expression, “Mimicry is the sincerest form of flattery”. If so, then Dr. David Steenblock surely is entitled to feel flattered as scores of integrative medical doctors and even some conventional ones began using natural and off-label therapies for stroke on the heels of his publicized pioneering work and successes with them. Among these:
Hyperbaric Oxygen Therapy (HBOT)
Beginning in 1989 Dr. Steenblock donned the mantle of pioneer among stroke-treating doctors by using hyperbaric oxygen therapy to treat stroke and was among the very first physicians to use HBOT to treat an acute stroke case and document a remarkable clinical response and turnaround. Dr. Steenblock also did trailblazing research-oriented clinical work involving the use of HBOT on cerebral palsy, autism and other neurologic diseases and conditions.
As you might expect, many critics and skeptics took exception to Dr. Steenblock’s use of hyperbaric oxygen therapy (HBOT) for chronic stroke. Quackwatch’s Stephen Barrett stated in 2010 that “It is true that strokes are caused by lack of oxygen to the brain. However, there is no scientific evidence that increasing oxygen delivery to the brain after an acute episode is over can stimulate cells to regenerate.”
This is not what Dr. Steenblock saw and documented.
Then, in 2013, a major randomized Israeli study was published in the journal PLOS Clinical Trials in which the authors reported that “… HBOT can lead to significant neurological improvements in post stroke patients even at chronic late stages”
SCORE: Steenblock +1, Skeptics -1
Stem Cell-Rich Bone Marrow Aspirate Concentrate (BMAC)
In early 2005 Dr. Steenblock began harvesting and infusing stem cell rich bone marrow aspirate concentrate (BMAC) along with FDA approved pharmaceutical stem cell activators to successfully treat a whole host of diseases and medical conditions including age-related macular degeneration, osteoarthritis, multiple sclerosis (MS), Amyotrophic Lateral Sclerosis (ALS), osteoporosis, spinal cord injury (SCI), Parkinson’s disease and COPD (Emphysema).
In the intervening years Dr. Steenblock and his medical team have done over 2000 BMAC treatments. What has emerged is that it is safe and effective in remediating stroke damage and other neurological maladies.
Critics, many being bench warming scientist and so-called bioethicists, objected to the use of adult stem cells including BMAC with all kinds of dire warnings about safety. Study after study appeared refuting this including one seminal one that was widely publicized this past spring: Stem cells can be safely infused in brain to promote stroke recovery, study finds: (May 21, 2015).
Quoting from this article:
“A yearlong study of stroke patients has found that stem cells from a patient’s bone marrow can be safely infused in the brain through the carotid artery to promote recovery(not a direct needle insertion but through a femoral artery catheter). Researchers at the Interdisciplinary Stem Cell Institute at the University of Miami Miller School of Medicine followed 48 patients, more than half of whom who were treated using stem cells, and found recovery along with no adverse side effects when compared with their counterparts.”
“Each patient was assessed at 24 hours post-procedure and again at 90, 180 and 365 days..”
“….both the placebo group and the treated group of patients were given traditional stroke-recovery therapy. Patients who were given the stem cell treatment were noted to recover motor skills and speech.”
“Yavagal explained the stem cells act as drug factories in the area of the brain damaged by the stroke, secreting a number of useful substances to promote recovery. The cells help repair damaged cells, including ones that encourage growth and act as anti-inflammatory aids. Some of the properties also act to salvage cells that are on the edge of dying, helping to preserve brain tissue and act as neuroprotectors.”
“Previously it was thought that they transform into neurons and brain tissue, but especially with bone marrow cells that does not seem to be the case,” Yavagal said. “The main effect seems to be through the supportive functions or nursing functions.”
Once again, science made a visionary and prophet of Dr. Steenblock. Or at least a very prescient in-office experimentalist! (And it is this sort of in-office experimentation which historians have clearly linked to medical progress).
Stem Cell Growth Factors
If you were stopped on the street by a TV reporter and asked, “What is a growth factor?”, what would your response likely be? Maybe you’d think, “Growth factor has the word ‘growth’ in it. A growth factor must thus influence..well….growth!” If so, you would not be far off the mark. Growth factors are molecules that bind to receptors on cells like keys in locks, which then set off a cascade of activity inside the cell that influences things like its growth, proliferation, and functioning. This exerts an influence on healing and regeneration.
Many growth factors impact stem cells in organs, tissues and the bone marrow. Some like granulocyte-colony stimulating factor (G-CSF) actually helps mobilize stem cells from the bone marrow while others like nerve growth factor (NGF) influences nerve cell (neuron) growth and survival.
Dr. Steenblock makes clinical use of a variety of growth factors that influence stem cells in ways that are beneficial (such as mobilizing revitalizing or encouraging specific activity). Among these are:
Neupogen® (Filgastrim): This growth factor is a manmade protein similar to granulocyte-colony stimulating factor (G-CSF) which stimulates production and mobilization of bone marrow stem cells.
Under what circumstances does Dr. Steenblock use Neupogen®? The main or primary one is to purge out old, inactive (senescent) bone marrow stem cells in older, sedentary and chronically ill people. The mobilization of these senescent stem cells prods their bone marrow to replace them with new, more vital stem cells.
It took some experimentation but what Dr. Steenblock discovered is that Neupogen® given for five (5) consecutive days mobilizes huge numbers of inactive bone marrow stem cells and switches the new stem cell manufacturing machinery into high gear.
Lab tests done on patient bone marrow who did the “Neupogen® purge” has shown that in two weeks time this revved up replacement activity typically produces upwards of ten (10) times more healthy stem cells than were present prior to the Neupogen® injections!
Once a patient’s bone marrow is brimming with new, healthier stem cells, Dr. Steenblock harvests some of this stem cell-rich marrow and does a bone marrow aspirate concentrate (BMAC) treatment.
Now, there is something you should know about bone marrow stem cells: They secrete a growth factor called “Nerve Growth Factor” which supports neuron growth and survival, suppresses inflammation, and also promotes angiogenesis or new blood vessel formation. NGF also fosters myelin repair (which is good news for those with multiple sclerosis which involves immune system attacks on the myelin sheath which insulates nerves) and may help a variety of psychiatric disorders plus dementia, depression, autism, and anorexia nervosa.
Dr. Steenblock also uses growth factor-rich platelet rich plasma (PRP). Where does this come from? PRP is actually created from a patient’s own blood. What Dr. Steenblock does is take a blood sample and then separates the platelets and growth factors using a centrifuge and, depending on the medical issue he is treating, either injects or infuses it directly into the diseased or damaged tissue (such as an arthritic joint) or mixes it with a patient’s own (harvested) bone marrow aspirate concentrate (BMAC) and then infuses it – or both. Platelet rich plasma (PRP) is rich in growth factors and other powerhouse compounds such as serotonin, fibronectin, adenosine diphosphate, thromboxane A, platelet factor 4, platelet derived growth factor, platelet activating factor and transforming growth factor beta, and SDF-1 which directly effects tissue repair as well as activates stem cells and encourage them to proliferate and grow wherever the PRP is placed.
Please contact us at 1-800-300-1063 or use the online form below to get more information about Dr. Steenblock and his unique blend of innovation and personalized regenerative medicine.