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Alzheimer’s & Dementia

Good News for people suffering from Alzheimer’s or Dementia

Vascular dementia as a diagnosis was essentially forgotten back in 1968 when pathologist Leopold Litz did a study of demented patients at a VA hospital. He found that most of these vascular dementia patients were, in fact, suffering from Alzheimer’s disease. 

However, his work was based solely on the presence of Alzheimer’s-linked neurofibrillary tangles, etc. and he did not examine the blood vessels and their endothelium closely, mainly because the available technology and the physical problems inherent in doing this type of study precluded this. From that time on almost all dementia cases have been thrown into the category or rubric “Alzheimer’s”, though this is dead wrong IMO. 
Most Alzheimer’s patients suffer from endothelial damage of their cerebral blood vessels and often have nocturnal hypoxemia as well.

Virtually no neurologist evaluates suspected Alzheimer’s patients using a nocturnal oximetry test which in my opinion is very important for this simple reason: episodes of nocturnal hypoxemia invariably lead to the development of amyloid plaque in vital areas of the brain.

Just putting these patients on night time oxygen can at times bring them back to normal – as long as they use it consistently. Chelation therapy will reverse Alzheimer’s pathology in about 60% of the cases. However, the only way this effect can be maintained is for chelation to be done every 3 weeks. 

The reason this works so well probably lies in the fact it decreases the patient’s red cell calcium content. Old blood vessels and their endothelial damage injures the red cell membranes and this allows calcium to accumulate within them. This increase in calcium causes rigidity of RBCs such that they cannot readily move through narrowed and diseased blood vessels which culminates in compromised tissue oxygenation.
Chelation removes the calcium from RBCs which means they can better transport oxygen for about 3 weeks after each chelation treatment. Stem cells help by fixing the endothelial damage and in this regard I have seen good results with these as well. The use of autologous adult stem cells is actually the easiest method of treating truly demented people since few of them can sit still for a 3 hour chelation iv. In addition: Heavy metals are often a part of the AD-generating equation as are chronic infections, all of which needs to be properly diagnosed and dealt with. Hormonal imbalances and addition of HGH, IGF-I, PRP, autologous conditioned serum, cerebrolysin, DMSO, methylcobalamin, folic acid, vitamins etc. all can helpful as well. In mild cases if you apply all of these there is a high probability of reversing the disease in almost 100% of AD sufferers.

This success rates drops to 80% or so in moderate cases and to 20% in advanced cases (The quantity of autologous adult stem cells used by most practitioners to treat severe AD is likely far lower than what is needed to effect remediation and a clinical turnaround. In all likelihood, massive, repeated doses are needed though no one has done this as part of any clinical trial that I am aware of.

Good News for people suffering from Alzheimer’s or Dementia

Vascular Contributions to Cognitive Impairment and Dementia

Good News for people suffering from Alzheimer’s or Dementia

Vascular contributions to cognitive impairment and dementia are important. Understanding of VCI has evolved substantially in recent years, based on preclinical, neuropathologic, neuroimaging, physiological, and epidemiological studies. Transdisciplinary, translational, and transactional approaches are recommended to further our understanding of this entity and to better characterize its neuropsychological profile. There is a need for prospective, quantitative, clinical-pathological-neuroimaging studies to improve knowledge of the pathological basis of neuroimaging change and the complex interplay between vascular and Alzheimer disease pathologies in the evolution of clinical VCI and Alzheimer disease. Long-term vascular risk marker interventional studies beginning as early as midlife may be required to prevent or postpone the onset of VCI and Alzheimer disease. Studies of intensive reduction of vascular risk factors in high-risk groups are another important avenue of research.

I bring this to my site to point out again that vascular (i.e. blood vessel disease) is a major component of Alzheimer’s and/or dementia and should be treated as soon as possible. I have developed a new unique formula for the treatment of vascular disease so if anyone wants to be a researcher and help determine if my product is better than anything else out there let me know and I will give it away for my direct out of pocket costs for the first 100 or so people who need treatment of their hypertension, kidney failure, atherosclerosis, dementia, and or Alzheimer’s.

Thanks. - Dr. S
Getting the Diagnosis Right
Testing & Assessments
Charting a Personalized Course
Stem Cells and Healing
Getting the Diagnosis Right

When a doctor sees a patient for the first time he will ask for copies of medical records as part of gathering information and data that, in combination with taking a medical history and doing relevant exams and tests, helps him arrive at a diagnosis (or confirm those previously made) and formulate a medical care plan. Dr. Steenblock does all this, yes, but goes beyond this. How so? He ferrets out previously undetected cause(s) and contributors of a person’s problems. This medical sleuthing or Sherlock Holmes mindset is what helps Dr. Steenblock come up with answers in situations where others have failed. Not surprisingly his track record of “discerning what has escaped other docs” has earned him the moniker “Doctor’s doctor” by his patients and a great many of his colleagues. How did Dr. Steenblock come to be a “medical sleuth”?

Medical sleuths are not born but made. The truly good ones have agile minds, intense curiosity, critical thinking skills and a sound medical and scientific education. Dr. Steenblock certainly has all this and more. His native abilities are reflected in a lifetime of accomplishments including spinning new ideas and inventions. His education and training are a matter of public record: A B.S. degree from Iowa State University in zoology, an M.S. in Biochemistry and Doctor of Osteopathy degree from the College of Osteopathic Medicine and Surgery in Des Moines, Iowa, followed by post-doctoral training that included three years at Case Western Reserve University, one year at the Oregon Health Sciences University and a clinical Rotating Internship at Providence Hospital in Seattle, Washington. Also — and very integral to doing medical detective work

— Dr. Steenblock spent years working in pathology, the science of studying and diagnosing disease.

Estimates vary but it appears around 4% of medical diagnoses are just plain wrong. Dr. Steenblock has run across this many times during his forty-four years of medical practice (40,000+ patients). Some of these patients had “consensus diagnoses” (a medical diagnosis made by 2 or more doctors) that turned out to be dead wrong. Needless to say, getting properly diagnosed helped get these folks on the right road. This is something Dr. Steenblock has in-mind with each and every patient who comes in to see him. Dr David Steenblock and Personalized Regenerative Medicine’s mission is to deliver advanced care for chronic and degenerative diseases.

Testing and Assessments

One of the central planks in Dr. David Steenblock’s practice of personalized medicine is to cover all the testing and diagnostic bases. The first step in this process is typically to do a complete physical examination, including routine lab work and any specialized testing Dr. Steenblock deems essential.

Given the fact that each person’s bone marrow stem cells play a crucial role in healing damaged or diseased organs and tissues, Dr. Steenblock also tests for things that interfere with stem cell mobilization as well as their vitality and activity. This includes testing to determine the presence and levels of heavy metals such as mercury, lead, cadmium, arsenic, etc. For adults, this is done using Dimercaptosuccinic acid (DMSA), which is an oral chelating agent that binds to heavy metals.  A one-time dose of DMSA is taken by the patient, followed by 6 hours of urine collection.  A sample is then sent to Doctor’s Data in Chicago for analysis.

Hormone deficiencies and excesses (e.g. hyperthyroidism, hypothyroidism, etc.) can impact stem cells, as well as the tissues into which they engraft.  This hormonal imbalance can bring about cellular changes that can dampen or otherwise impede stem cell activity. Dr. Steenblock prescribes hormone panel tests that measure such hormones as DHEA, IGF-1hGH, estrogen, progesterone and testosterone and prolactin.

Physical stressors including, but not limited to hypoxia (low blood and tissue oxygen levels), intermittent hypoxia, nocturnal hypoxemia (serious drops in tissue oxygen levels during sleep), chronic persistent hypoxia secondary to COPD (emphysema), metabolic acidosis (happens in poorly controlled diabetes) or other noxious tissue conditions are also deterrents for stem cell activity. To detect & measure the extent of these Dr. Steenblock runs tests that measure carbon dioxide (CO2) blood levels, LDH isoenzymes & lactic acidpyruvic acid levels, salivary and urine pH. In addition, Dr. Steenblock may also order a nocturnal oximetry test, electrocardiogram (EKG), and pulmonary function studies.

Dr. Steenblock looks for active infections whether bacterial, viral, or mycoplasma in nature in gums, sinuses, organs or other tissues, plus smoldering or hard-to-detect low grade infections, especially those caused by certain herpes viruses and retroviruses. Tests that Dr. Steenblock may utilize, when indicated, include a computed tomography (CT) scan of the lungs and sinuses to rule out sinus infections and a Comprehensive Digestive Stool Analysis (CDSA) plus Parasite test to rule out intestinal issues, including disturbances in bowel ecology.

These sorts of infections tend to attract stem cells, including those that would ordinarily wind up supporting the body’s own repair and restoration processes.

Poor nutrition, consumption of unhealthy fats and simple sugars, binge or heavy drinking, consumption of carbonated beverages (especially those that are sugar-laden), overconsumption of caffeine, and so on, can make many medical conditions worse. In addition, lack of certain nutrients, like vitamin D, as well as excess amounts of others, such as vitamins K and A, can all impede or interfere with the viability & activity of stem cells. Generally, Dr. Steenblock conducts a systematic review of a patient’s diet, which may require the patient to keep a food diary for a period of time.  In addition, specialized testing may be done to more accurately determine the patient’s nutritional needs.

Drug interactions and excessive or wrong drug choices, including herbal supplements, vitamins and minerals can potentially create medical problems or complicate and negatively impact various diseases and conditions, not to mention adversely affecting stem cell growth, proliferation or function.  Therefore, Dr. Steenblock typically reviews each patient’s past & present prescription and over-the-counter (OTC) pharmaceuticals, herbs, herbal teas and supplements, vitamins and minerals, as well as illicit drugs in order to be able to make the safest and most effective decisions for the patient’s regenerative health.

Dr. Steenblock makes use of various highly sophisticated tests to help gauge such things as how a patient is likely to respond to a particular ordered medication, or ascertaining a patient’s risk of developing certain types of chronic diseases in the future. One comprehensive genetics test Dr. Steenblock often orders for his patients is 23andme. This kind of testing makes it possible for him to individualize many aspects of the care he provides.

In addition to the aforementioned tests, Dr. Steenblock may also order some or all of the following labs to help complete his assessment and develop a more personalized treatment plan:   Complete Blood Count (CBC), Erythrocyte Sedimentation Rate (ESR), C-Reactive Protein (CRP), thyroid paneluric acidammonia (brain cases), erythropoietin (EPO) test if anemia is present, reticulocyte count, iron, Total iron-binding capacity test (TIBC)oxygen % saturation, copper, ceruloplasmin,  Antinuclear Antibody Testwith reflex, and urine organic acids.

Charting a Personalized Course

Putting it all together: Creating a Personalized Treatment Plan

Once a patient’s diagnosis is confirmed, modified or even overturned and the results of all tests ordered are in, Dr. Steenblock can then put all the pieces together create a personalized treatment plan. This simply means that therapies and treatments are matched to the individual and their unique biochemical and genetic make-up, as well as other characteristics and features, including those of their particular medical challenges. This process helps increase the patient’s potential for optimal outcomes and significant clinical improvements.

Treatment plans will typically include strategies such as:

  • Addressing heavy metal toxicity using chelation therapy
  • Balancing hormone levels through hormone replacement therapy
  • Treating various infections using antimicrobial therapies
  • Addressing nutritional deficiencies and unique dietary needs through individualized therapeutic diet plans, oral supplements, and IV nutritional therapies
  • Prescribing or changing pharmaceutical medications and nutritional supplements in order to maximize their benefits for health and regenerative capacity, as well as minimize any potential adverse reactions or interactions

In addition to the above listed strategies, treatment modalities such as those listed below may also be incorporated as part of the patient’s personalized care plans:

  • Hyperbaric oxygen therapy (HBOT)
  • Periodic acceleration therapy (PAT)
  • Pulsed magnetic field therapy (PMFT)
  • Hyperthermia
  • External counterpulsation
  • Hyperthermic Ozone and Carbonic Acid Transdermal Therapy (HOCATT
  • IV or Oral Chelation
  • Nutritional or Other Intravenous Therapies
  • Platelet Rich Plasma Therapy
  • Stem Cell Therapies

Some the health challenges for which Dr. Steenblock has produced effective, personalized treatment programs, include:

  • ALS (Amyotrophic Lateral Sclerosis)
  • Multiple Sclerosis (MS)
  • Parkinson’s Disease (PD)
  • Cerebral Palsy (CP)
  • Alzheimer’s Disease (AD)
  • Stroke
  • Traumatic Brain Injury (TBI)
  • Cardiovascular Conditions
  • COPD (Emphysema, Bronchitis, Asthma)
  • Lupus
  • Arthritis

Stem Cells and Healing

Dr. Steenblock’s personal and medical career can be summed up with one word: Innovation.  He has, in fact, spent over four decades doing the sort of in-office exploration and experimentation that has traditionally driven progress in medical science. And, while most doctors adhere to “formulaic treatment approaches” that enjoy official approval, medical innovators like Dr. Steenblock use drugs off-label and employ established & new therapies in unique ways and combinations.

In addition, Dr. Steenblock focuses on creating individualized patient programs that take into account unique variations in each patient’s biochemistry, predispositions, disease & bodily vulnerabilities, deficiencies and more. These are all painstakingly identified and then addressed or otherwise therapeutically exploited.

As part of Dr. Steenblock’s quest to innovate and customize patient care, he found that many chronic and degenerative diseases are slowed, halted and even reversed when nature’s own repair & restoration mechanism, namely adult (nonembryonic) stem cells, is augmented. This makes sense really as disease prods the sufferer’s body to attempt to repair the damage by activating stem cells residing in the affected tissues. This process also results in the mobilization of stem cells from the bone marrow and their attraction to diseased  areas. Unfortunately, these stem cells are not always up to the job of repair and regeneration especially when it comes to aging, sedentary or chronically ill people, mainly because their marrow tends to harbor large numbers of senescent (inactive) stem cells. This is where Dr. Steenblock’s penchant to innovate resulted an elegant solution: In-a-word, Neupogen®.  He found that by giving these patients injections of the FDA approved stem cell mobilizing drug Neupogen® for five (5) consecutive days, their marrow purged out the senescent stem cells and then created up to ten times as many healthier, more activate stem cells.

Once a patient’s marrow is brimming with new, more active stem cells, Dr. Steenblock removes a small quantity and uses this to produce what is referred to as bone marrow aspirate concentrate (BMAC), which he then administers back to the patient.

Connect with us to request more information about Dr. Steenblock and his celebrated blend of innovation and personalized regenerative medicine, including his use of stem cells.

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